Brew pause option to have a cup before brewing is completed
This classically designed coffeemaker is accented with stainless steel for a look that is sure to enhance your countertop. The 12 cup carafe features an ergonomic handle, dripless spout and knuckle guard for comfortable, drip-free pouring. Fully automatic, the DCC-1100 has 24-hour programmability and 1 to 4 cup setting for those times you don't need a full pot of coffee. The Brew pause feature lets you pour a cup before brewing is completed, while the gold tone coffee filter and charcoal water filter ensure fresh, delicious tasting coffee.
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Apoptosis may contribute to false-positive results in the in vitro micronucleus test performed in extreme osmolality, ionic strength and pH conditions ... Toxicology and Environmental Mutagenesis]
This digital document is a journal article from Mut.Res.-Genetic Toxicology and Environmental Mutagenesis, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.
Description: Conditions in which clastogens produce positive responses have been increasingly challenged, and several situations have been described in which clastogenic responses would be considered not to be relevant. For example, extreme culture conditions lead to high variations of pH, osmolality or ionic strength. Apoptosis is induced in extreme culture conditions and contributes to false-positive results in the in vitro micronucleus test performed with CTLL-2 cells. These cells can enter apoptosis when exposed to apoptosis stimuli or after IL-2 deprivation, whereas the CTLL-2 Bcl2 cell line is protected from apoptosis due to the over-expression of the apoptosis inhibitor Bcl2 in bcl2-transfected CTLL-2 cells. The two cell lines were treated in extreme culture conditions of either pH or osmolality or were submitted to high ionic strength. The apoptosis level was measured in parallel with the in vitro micronucleus test using the annexin V-FITC method. Data obtained in the two cell lines suggested that apoptosis caused by extreme culture condition induces the formation of micronucleated cells, which leads to false-positive results in the in vitro micronucleus test.
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Extreme Networks Announces 300 Customers for its All-Ethernet Open Fabric
Extreme Networks Open Fabric is based on 40 GbE network ... including network design and actual results of use of the product in different environments. We undertake no obligation to update the forward-looking information in this release.
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